Simultaneous separation of ciprofloxacin, norfloxacin and ofloxacin by micellar electrokinetic chromatography

Simultaneous Separation of Ciprofloxacin, Norfloxacin and Ofloxacin by Micellar Electrokinetic Chromatography

Este trabalho descreve o desenvolvimento de um método simples de eletroforese capilar (EC) para determinação simultânea dos três derivados mais frequentemente usados da fluoroquinolona: ciprofloxacina, norfloxacina e ofloxacina. Devido às características estruturais e físico-químicas muito semelhantes, ciprofloxacina e norfloxacina não podem ser separadas pelo método clássico de eletroforese ca...

Separation of dithiocarbamate metal complexes by micellar electrokinetic chromatography

Separation of a number of transition metal complexes with bis(2-hydroxyethyl)dithiocarbamate (HEDTC) by micellar electrokinetic capillary chromatography (MEKC) with direct photometric detection was investigated. Pre-capillary complexation was shown to be superior to on-capillary complexation in terms of the number of metals ions which could be detected and their peak shapes, enabling analysis o...

Separation of preservatives in cosmetic products by micellar electrokinetic chromatography.

This paper describes the methodological optimization and validation of a simple micellar electrokinetic chromatography for the rapid simultaneous separation of 2-methyl-4-isothiazolin-3-one, methylparaben, ethylparaben, propylparaben, and butylparaben. By using a 30 mM phosphate buffer (pH 7.2) containing 30 mM sodium dodecyl sulfate (SDS), an applied voltage of 10 kV and a separation temperatu...

Micellar electrokinetic chromatography.

Micellar electrokinetic chromatography (MEKC) separation of furanonaphthoquinones from Tabebuia impetiginosa.

The separation of nine furanonaphthoquinones by micellar electrokinetic chromatography (MEKC) is described. The running electrolytes used in this method were 0.03 M sodium dodecyl sulphate (SDS) in 0.09 M borate buffer (pH 9) containing 10% methanol, with an applied voltage of 20 kV. Application of this technique in the determination of the main furanonaphthoquinones, 5-hydroxy-2-(1-hydroxyethy...